In May 1993, an outbreak of an unexplained pulmonary illness occurred in the southwestern United States

Rat Control   

                                                Rat disease: World's first human case discovered in Hong Kong

09/29/2018

Here we go again!

The “First” Outbreak- Hantavirus

In May 1993, an outbreak of an unexplained pulmonary illness occurred in the southwestern United States, in an area shared by Arizona, New Mexico, Colorado and Utah known as “The Four Corners”. A young, physically fit Navajo man suffering from shortness of breath was rushed to a hospital in New Mexico and died very rapidly.

While reviewing the results of the case, medical personnel discovered that the young man’s fiancée had died a few days before after showing similar symptoms, a piece of information that proved key to discovering the disease. As Dr. James Cheek of the Indian Health Service (IHS) noted, “I think if it hadn’t been for that initial pair of people that became sick within a week of each other, we never would have discovered the illness at all”.

After the virus was identified, doctors starting finding it in rodents all across the United States and Europe. Turns out it was not just a local issue. 10 years ago, in New York City, The health department found a dozen different previously unknown viruses being carried by rats in the city. Since then those viruses have been found in rats in Chicago, Los Angeles and in East Asia. Again, not a local issue.    

Now another new disease has been discovered that’s carried by rats. The following is a reprint of a medical article out of Hong Kong. Since rats are native to this area, and history tells us the world’s rats originated from Asia, it’s highly likely our rats will probably be found to carry this newly found virus  

For the first time, a case of rat hepatitis E has been discovered in a human in Hong Kong.

A 56-year-old man has been diagnosed with the disease, researchers from the University of Hong Kong said. It was not previously known the disease could be passed from rats to humans.

"Previous laboratory experiments have found that rat hepatitis E virus cannot be transmitted to monkeys, and human hepatitis A virus cannot be transmitted to rats," said Dr. Siddharth Sridhar, clinical assistant professor at the University of Hong Kong, explaining that monkeys are very close to humans when it comes to disease susceptibility.

The risk of rat hepatitis E affecting humans has been underestimated, Sridhar said during a news conference.

The man developed the disease after undergoing a liver transplant following chronic infection with hepatitis B. He continued to show signs of abnormal liver function, said Sridhar, with no obvious cause.

Investigations revealed signs of an immune response to hepatitis E, which is a major cause of viral hepatitis in humans all around the world, he said. But tests for the human form of the virus came back negative.

Genetic sequencing of the virus infecting the man then revealed similarities with the rat form of the disease and the man was given antiviral treatment.

"The patient is cured, as of this stage we can no longer detect the virus in any clinical specimen," said Sridhar.

The team then wanted to know how the disease was able to cross over from rats into a human and believe the man caught the disease from rats infesting a rubbish chute near his home.

"Rat hepatitis E virus now joins this list of infections as an important pathogen that may be transmitted from rats to humans," said Sridhar.

The team believes the most important control measure would be to limit the rat population and ensure there is no rubbish for rats to feed on.

Hepatitis causes inflammation of the liver, with various viruses that cause it. Most commonly, hepatitis A, B and C spread through either contaminated food and water or blood and other body fluids, depending on the virus. 

The human form of hepatitis E is typically transmitted through contaminated water, and is estimated to infect 20 million people worldwide, resulting in 3.3 million people showing symptoms each year, according to the World Health Organization. It caused approximately 44,000 deaths in 2015, making up 3.3% of all deaths from viral hepatitis.

The animal form of the disease is thought to infect wild boars, domestic pigs and deer, as well as rats and other rodents.